OVERVIEW
Wake Research Associates is an independent multi-center clinical research site designed to
work closely with and to meet the needs of the pharmaceutical industry and clinical
research organizations. WRA was founded by, and continues to be affiliated with, a large
private group practice of internal medicine and subspecialties drawing from a patient
database of 80,000.. This group practice currently has a patient population of
approximately 80,000 and is associated with Key Physicians, a primary care physicians
network (IPA). WRA is also affiliated with 127 subspecialty physicians in the Raleigh
area.
We have over 20 years of clinical research experience. Our board certified physicians have
completed more than 1,300 successful clinical trials. Clinical trials at our site are
always completed on time and with accuracy; we consistently exceed sponsor expectation for
integrity, subject enrollment, human protection and expeditious delivery of accurate
evaluable data.
WRA is a unique and innovative resource for
Phase I-IV clinical trials. Our site is known for effectively combining strategic business
development and retention with high quality clinical research procedures. Our approach is
uncompromising – each study conducted at our site is carefully planned and executed
according to regulations with superior quality."
MANAGEMENT
Charles Barish, MD
President
Ella Grach, MD
Executive Medical Director
Marion Peoples
Site Manager
FACILITY DESCRIPTION
• Certified Endoscopy unit (Colonoscopy, Upper Endoscopy, Sigmoidoscopy and Liver
Biopsies)
• Gastrointestinal Lab (24 hour / pH monitoring) & Virtual Capsule Endoscopy
• Certified Diagnostic Laboratory
• Radiology Department with Bone Densitometer, Ultrasound Unit and CT Scanner
• Cardiovascular Testing: Heart Station, including EKG’s, Echo-EKG, Treadmills,
Holter Monitoring, Ambulatory Blood Pressure Monitoring and Nuclear Cardioscanner
• Complete Pulmonary Unit with Spirometry, Peak Flow Monitoring and Survey System
Plus
• Certified Mammography Unit
• Secured Investigational Drug Storage Facilities
• Facilities for Provocative Meal Studies
• Facilities for Extended-Stay Pharmacokinetic Studies
• Sleep Lab (EEG, Polysomnography studies)
• Electronic Data Capture (EDC) Capability
• 28 exam rooms
• 5 monitoring rooms with modem, access to
phone, fax and copier
Sleep Lab includes:
• Experienced Study Coordinators
• Expert psychometricians and raters for cognitive testing
• Fully equipped rooms for sleep studies including polysomnography, multiple sleep
latency testing, and
maintenance of wakefulness
• Shower facilities
• Certified Sleep Technicians
• ECG and EEG
• Weight Management and Nutrition Center
• Phase I and Pharmocokinetic Unit with infusion capabilities, private rooms, shower
and TV
Affiliated Hospitals
Rex Hospital
Wake Medical Center
Western Wake Medical Center
Affiliated Sites
Raleigh, N. C.
Internal medicine practice
Gynecology practice
Urology practice
Psychiatry practice
Gastroenterology practice
AREAS OF RESEARCH
WRA has conducted Phase I-IV studies including:
• Acne
• Actinic Keratosis
• ADHD
• Alzheimers
• Anemia
• Anxiety
• Atopic Dermatitis
• Avian Influenza
• Chronic Hand Dermatitis
• Colorectal Cancer Screening
• Common Cold
• Contraception
• COPD
• Crohns disease
• Depression
• Diabetes (Type I and II)
• Diabetic Neuropathy
• Dyspepsia
• Endometriosis
• Erosive Esophagitis
• Exacerbation of Chronic Bronchitis
• Fatigue
• Female Sexual Dysfunction
• Fibroids
• Fibromyalgia
• GERD
• Healthy Volunteer studies
• Hepatitis C
• Hormone Replacement
• Hot Flashes
• HPV / Genital Warts |
• HSDD
• Hypercholesterolemia
• Hypertension (including ABPM)
• Incontinence
• Influenza
• Influenza Prevention
• Irritable Bowel Syndrome
• Insomnia
• Lower Back Pain
• Male Erectile Dysfunction
• Menstrual Migraines
• Metabolic Syndrome
• Migraines
• Nutrition
• Obesity
• Onychomycosis
• Osteoarthritis
• Osteoporosis
• Overactive Bladder
• Pneumonia
• Psoriasis
• Ragweed
• Rapid Ejaculation
• Rheumatoid Arthritis
• Rosacea
• Smoking Cessation
• Sleep Disorders
• Tinea Capitis
• Ulcerative Colitis
• Urinary Tract Infection
• Warts |
RESEARCH STAFF
Our employees are dedicated to providing excellent service with the ultimate goal of
improving patient care. Wake Research Associates brings the medical expertise and
leadership, enthusiasm, and professionalism to all of our projects.
• 12 Full time Clinical Research Coordinators including 4 RNs, 1 LPN, 1 CMA and 1 MA
• 3 Research Assistants
• Regulatory Specialist
• 1 Finance Associate
• 2 Administrative Assistants
• 3 Dedicated Patient Recruiters
• Quality Assurance
INVESTIGATORS
Gastroenterology
Principal Investigator:
Charles Franklin Barish, MD, FACP, FACG
8 physician-investigators
Psychiatry
Principal Investigator:
Susan L. Eder, M.D.
3 physician-investigators
2 psychologists
Women's Health & Gynecology
Principal Investigator:
Pouru Bhiwandi, MD
3 physician-investigators
Dermatology
Principal Investigator
Adnan Nasir, M.D., Ph.D.
Internal Medicine
Principal Investigator:
Wayne Lee Harper, MD
18 physician-investigators |
Pulmonary
Principal Investigator:
Jonathan Flescher, M.D., F.C.C.P.
2 physician-investigators
Nutrition
Mary Ann Pollock, RD, PhD
Debrah Barish, RD
Geriatrics
Principal Investigator:
Arrind N. Jariwala, MD
18 physician-investigators
Neuroscience
Principal Investigator:
Singar Jagadeesan, MD
8 physician-investigators |
